The political subjugation and suspension of othered bodies between life and death, extensions of biopower, and advancements in biotechnology and artificial intelligence today throw life's definitions and valuations into high relief. Through the original pairing of Bonnet and King's work, De Anima examines life and its semblance at this moment of heightened pressure on epistemic, existential, and technological questions of animacy. The catalogue features newly commissioned texts by Pamela H. Smith, founding director of The Making and Knowing Project at Columbia University, Seth Low Professor of History, and Director of the Center for Science and Society; Kenneth Gross, Professor of English at the University of Rochester and a scholar of Renaissance and modern literature; acclaimed novelist Emma Cline; Swiss Institute Director Stefanie Hessler, as well as a conversation between the artists. Together, these contributions push against the boundaries between life and nonlife, vitality and passivity, and substance and gesture, in relation to art, technology, and gender. Louise Bonnet (*1970, Geneva) lives and works in Los Angeles, California Elizabeth King (*1950, Ann Arbor) lives and works in Richmond, Virginia